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Synthesis of proposed chain-elongation intermediates of the monensin biosynthetic pathway

✍ Scribed by Block, Michael H.; Cane, David E.

Book ID
118060142
Publisher
American Chemical Society
Year
1988
Tongue
English
Weight
814 KB
Volume
53
Category
Article
ISSN
0022-3263

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## Abstract A fast and efficient route to ^32^P‐labeled intermediates on the purine biosynthetic pathway is described. Adenosine kinase catalyzes the phosphorylation of 5‐aminoimidazole‐4‐carboxamide ribonucleoside (AICARs) to give [^32^P]‐5‐aminoimidazole‐4‐carboxamide ribonucleotide (AICAR). This