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Synthesis of “pre-presqualene′, a predicated intermediate in presqualene biosynthesis, and of prenylogues

✍ Scribed by Ian Shirley; Ian H. Smith; Donald A. Whiting


Book ID
104220642
Publisher
Elsevier Science
Year
1982
Tongue
French
Weight
234 KB
Volume
23
Category
Article
ISSN
0040-4039

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✦ Synopsis


The synthesis is reported, using deconjugative addition, of the E-and Zdials (15g) and ( 16g) , postulated intermediates8 in presqualene biosynthesis.


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✍ Müller, Thomas ;Schmidt, Richard R. 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 943 KB

## Abstract The synthesis of disodium (6‐deoxy‐α‐D‐__ribo__‐hexopyran‐3‐ulosyl) (2′‐deoxythymidin‐5′‐yl) diphosphate (1) is described. To this end, D‐glucose is transformed into known furanose derivative 2 possessing a 3‐__C__‐methylene group as latent functionality for 3‐ulose generation. From 2,