✦ LIBER ✦

Synthesis of potential selective cox-2 enzyme inhibitors derived from ethyl ester of 2-isothiocyanato-5-phenyl-3-thiophenecarboxylic acid

✍ Scribed by Andrea Santagati; Agostino Marrazzo; Giuseppe Granata

Book ID: 102340986
Publisher: Journal of Heterocyclic Chemistry
Year: 2003
Tongue: English
Weight: 67 KB
Volume: 40
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570400519

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✦ Synopsis

Abstract

Derivatives containing the thieno[2,3‐d]pyrimidin‐4‐one system, potential selective COX‐2 inhibitors, were prepared starting from ethyl ester of 2‐isothiocyanato‐5‐phenyl‐3‐thiophenecarboxylic acid (2); their structural elucidation is also reported.

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