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Synthesis of polytripeptide (pro-ser-gly)n, modeling the collagen type of structure

โœ Scribed by V. A. Shibnev; Sh. Kh. Khalikov; M. P. Finogenova; K. T. Poroshin


Book ID
112422938
Publisher
Springer
Year
1970
Tongue
English
Weight
236 KB
Volume
19
Category
Article
ISSN
1573-9171

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The synthesis of the tripeptide polymers (Pro-Gly-Pro) n, (Pro-Pro-Gly) n, and (Gly-Pro-Pro),, is described, with particular attention to procedures which favor the efficient insertion of radioactive proline in either of the two proline positions 'X" or "Yr in the internal sequence, Gly-X-Y. By our

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## Synopsis Conformational analysis of triple helices of a type of collagen was performed with typical collagen tripeptide sequences based on Gly-Pro-Ala, Gly-Ala-Hyp, and Gly-Ala-Ala. During energy minimization, the possibility of continual deformation of the pyrrolidine cycle was taken into acco

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