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Synthesis of Poly(propylene glycol)-block-Polyethylenimine Triblock Copolymers for the Delivery of Nucleic Acids

✍ Scribed by Blandine Brissault; Christian Leborgne; Daniel Scherman; Christine Guis; Antoine Kichler


Book ID
102934875
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
648 KB
Volume
11
Category
Article
ISSN
1616-5187

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✦ Synopsis


a Supporting Information is


πŸ“œ SIMILAR VOLUMES


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## Abstract The amphiphilic triblock copolymer PLA__‐b‐__PLL__‐b‐__MPEG is prepared in three steps through acylation coupling between the terminal amino groups of PLA__‐b‐__PZLL‐NH~2~ and carboxyl‐terminal MPEG, followed by the deprotection of amines. The block copolymers are characterized via FT‐I

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## Abstract **Summary:** Bis(hydroxy)telechelic bisphenol A polycarbonate (PC) was prepared via melt polycondensation of bisphenol A (BPA) and diphenyl carbonate (DPC) using lanthanum(III) acetylacetonate as a catalyst for transesterification. Subsequently, the polycarbonate was converted to a bifu

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Hyper-branched polyethylenimine grafted polycaprolactone block mono-methoxyl poly (ethylene glycol) copolymer (hy-PEI-g-PCL-b-mPEG) was obtained through the conjugation of mPEG-PCL with hyperbranched PEI (hy-PEI) based on the Michael addition. mPEG-PCL was synthesized by ring-opening polymerization