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Synthesis of polyhydroxysterols (IV): synthesis of 24-methylene-cholesta-3β,5α,6β,19-tetrol, a cytotoxic natural hydroxylated sterol

✍ Scribed by Weigang Lu; Longmei Zeng; Jingyu Su


Book ID
116891691
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
85 KB
Volume
69
Category
Article
ISSN
0039-128X

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✍ B. RUAN; W. K. WILSON; G. J. JUN. SCHROEPFER 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 38 KB 👁 1 views

An Alternative Synthesis of 4,4-Dimethyl-5α-cholesta-8,14,24-trien-3β-ol, an Intermediate in Sterol Biosynthesis and a Reported Activator of Meiosis and of Nuclear Orphan Receptor LXRα. -The title compound (V) is synthesized by a simple six-step procedure. A key step in this synthesis is the highly