✦ LIBER ✦
ChemInform Abstract: An Alternative Synthesis of 4,4-Dimethyl-5α-cholesta-8,14,24-trien-3β-ol, an Intermediate in Sterol Biosynthesis and a Reported Activator of Meiosis and of Nuclear Orphan Receptor LXRα.
✍ Scribed by B. RUAN; W. K. WILSON; G. J. JUN. SCHROEPFER
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 38 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
An Alternative Synthesis of 4,4-Dimethyl-5α-cholesta-8,14,24-trien-3β-ol, an Intermediate in Sterol Biosynthesis and a Reported Activator of Meiosis and of Nuclear Orphan Receptor LXRα.
-The title compound (V) is synthesized by a simple six-step procedure. A key step in this synthesis is the highly efficient and specific oxidation of the saturated side chain of (I). -(RUAN, B.;