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Synthesis of polyfunctionally substituted heteroaromatic compounds via benzotriazolyl chalcones with antimicrobial and antifungal activities

✍ Scribed by Fatima Al-Omran; Adel Abou El-Khair

Publisher: Journal of Heterocyclic Chemistry
Year: 2004
Tongue: English
Weight: 275 KB
Volume: 41
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570410304

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✦ Synopsis

Abstract

The utility of both 3‐(1‐benzotriazolyl) chalcone derivatives 3a‐c and 2‐(1‐benzotriazolyl)‐1,4‐pentadien‐3‐one (18) in the synthesis of some new 2‐(1__H__)‐pyridone, pyridine, pyrazole and isoxazole derivatives is reported. Antimicrobial and antifungal screening of some selected examples from the synthesized products were carried out. The structure of the newly synthesized compounds was elucidated by elemental analysis, ir, ^1^H and ^13^C nmr investigations.

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