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Synthesis of Polyfunctionalized Bicyclo[5.3.1]undecadiene Ring Systems Using a Two-Carbon Ring-Expansion of Cyclobutene Intermediates

✍ Scribed by Gaëtan Mislin; Michel Miesch


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
338 KB
Volume
2001
Category
Article
ISSN
1434-193X

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The Cyclopropylalkylidenecyclopropane Thermal Double Ring Expansion. A Novel Route to the Bicyclo[5.3.1]undecane Skeleton of the AB Ring System of Taxanes. -The mechanism of the reaction is explained by the initial formation of a diradical followed by opening to a homoallylic biradical which closes