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Synthesis of plasmin substrates and relationship between their structure and plasmin activity

✍ Scribed by Okada, Yoshio ;Tsuda, Yuko ;Teno, Naoki ;Wanaka, Keiko ;Sasaki, Kuniko ;Hijikata, Akiko ;Naito, Taketoshi ;Okamoto, Shosuke

Book ID
115098480
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
352 KB
Volume
27
Category
Article
ISSN
0367-8377

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Fluorogenic peptide amide substrates for
Fluorogenic peptide amide substrates for the estimation of plasminogen activators and plasmin
✍ W. Nieuwenhuizen; G. Wijngaards; E. Groeneveld πŸ“‚ Article πŸ“… 1977 πŸ› Elsevier Science 🌐 English βš– 312 KB

Fluorogenic substrates, i.e., t-BOC-L-valyl-glycyl-L-arginine P-naphthylamide (II) and L-valyl-glycyl-L-arginine P-naphthylamide (III) were synthesized. The kinetic constants of the hydrolysis of these substrates and of commercial glycyl-L-arginine P-naphthylamide (I) by plasmin, urokinase, and plas