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Synthesis of phosphopeptides by the multipin method: Evaluation of coupling methods for the incorporation of Fmoc-Tyr(PO3Bzl,H)-OH, Fmoc-Ser(PO3Bzl,H)-OH and Fmoc-Thr(PO3Bzl,H)-OH

✍ Scribed by John W. Perich; Nicholas J. Ede; Susan Eagle; Andrew M. Bray


Book ID
105576551
Publisher
Springer Netherlands
Year
1999
Tongue
English
Weight
484 KB
Volume
6
Category
Article
ISSN
1573-3149

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Evaluation of coupling conditions for th
✍ Carlos García-Echeverría 📂 Article 📅 1996 🏛 Springer Netherlands 🌐 English ⚖ 305 KB

In order to minimise the formation of the pyrophosphate derivative of the target peptide when side-chainunprotected phopshotyrosine is used in solid-phase peptide synthesis, this building block can be incorporated using benzotriazolyloxy-tris-(dimethylamino)phosphonium hexafluorophosphate/1-hydroxyb