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Synthesis of phosphonate analogues of sphinganine-1-phosphate and sphingosine-1-phosphate

โœ Scribed by Andreas Schick; Thomas Kolter; Athanassios Giannis; Konrad Sandhoff


Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
710 KB
Volume
51
Category
Article
ISSN
0040-4020

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๐Ÿ“œ SIMILAR VOLUMES


Efficient synthesis of sphingosine-1-pho
โœ Kratzer, Bernd ;Schmidt, Richard R. ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 839 KB

## Abstract Readily available Dโ€__erythro__โ€azidosphingosine is transformed into 3โ€__O__โ€silylโ€protected derivative 6. Reduction of the azido group afforded 3โ€__O__โ€silylโ€protected sphingosine 7 which was either converted into __N__โ€Fmocโ€protected derivative 8 or via Nโ€acylation into ceramide deriv