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Synthesis of phosphocarnitine

✍ Scribed by Elżbieta Tadeusiak; Bożena Krawiecka; Jan Michalski


Book ID
104260808
Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
98 KB
Volume
40
Category
Article
ISSN
0040-4039

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✦ Synopsis


Stereoselective synthesis of phosphocamitine has been achieved for the first time starting from R(-)epichlorohydrin.


📜 SIMILAR VOLUMES


ChemInform Abstract: Synthesis of Phosph
✍ Elzbieta Tadeusiak; Bozena Krawiecka; Jan Michalski 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 27 KB

Synthesis of Phosphocarnitine. -The reaction of (R)-epichlorohydrin (I) with phosphite (II) gives the phosphonic ester (III). The latter is transformed into the optically active phosphocarnitine salt (VII) by dealkylation, replacement of chloride with trimethylamine and ion exchange with potassium