## Abstract The synthesis and characterization of three new 4‐pyridyl porphyrin‐peptidyl‐phosphonate compounds, containing a diphenyl 3‐pyridylmethyl‐phosphonate moiety, is described in this article. Nitrogen atoms in the pyridine rings of the obtained compounds were alkylated using methyl iodide,
Synthesis of peptidyl phosphonates containing 5-(4′-carboxyphenyl)-10,15,20-tritolylporphyrin
✍ Scribed by Jan Habdas; Bogdan Boduszek
- Book ID
- 102231927
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 146 KB
- Volume
- 19
- Category
- Article
- ISSN
- 1042-7163
- DOI
- 10.1002/hc.20407
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✦ Synopsis
Abstract
The synthesis and characterization of three new porphyrin‐peptidyl‐phosphonate derivatives, containing a diphenyl 3‐pyridylmethyl‐phosphonate moiety, is described. These compounds could serve as potential photosensitizers for the PDT method of tumor therapy and displayed activity as inhibitors of aminopeptidase N. © 2008 Wiley Periodicals, Inc. Heteroatom Chem 19:107–111, 2008; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20407
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The synthesis and characterization of new alkali-soluble osmium tetraphenylporphyrinates, complexes of the 5,10,15,20-tetrakis(4-carboxyphenyl)porphyrin Os ( tH ~4~ cpp ) L ~2~ and Os ( tH ~4~ cpp ) LL ' (2a–j), is described. 2a–j are obtained from the corresponding new osmium porphyrinates Os ( tme