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Synthesis of peptide dendrimers based on a β-cyclodextrin core with guest binding ability

✍ Scribed by Abdullah M.A. Muhanna; Emilia Ortiz-Salmerón; Luis Garcı́a-Fuentes; Juan J. Giménez-Martı́nez; Antonio Vargas-Berenguel

Publisher: Elsevier Science
Year: 2003
Tongue: French
Weight: 247 KB
Volume: 44
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(03)01432-1

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✦ Synopsis

The synthesis of three first-order dendrimers based on a b-cyclodextrin core containing fourteen Val, Phe and Val-Phe residues is described. The guest binding ability of the tetradecavalent peptidyl b-cyclodextrin derivative has been tested by calorimetric titration and the thermodynamic parameters for the complex formation with adamantanecarboxylic acid were obtained.

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