Synthesis of Peptide Alcohols on the Basis of an O–N Acyl-Transfer Reaction
✍ Scribed by Julien Tailhades; Marie-Aude Gidel; Benjamin Grossi; Jennifer Lécaillon; Luc Brunel; Gilles Subra; Jean Martinez; Muriel Amblard
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 582 KB
- Volume
- 122
- Category
- Article
- ISSN
- 0044-8249
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## Abstract An efficient method of peptide thioester synthesis is described. The reaction is based on an __N__‐4,5‐dimethoxy‐2‐mercaptobenzyl (Dmmb) auxiliary‐assisted __N__‐__S__ acyl shift reaction after assembling a peptide chain by Fmoc‐solid phase peptide synthesis. The Dmmb‐assisted __N__‐__S
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