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Synthesis of pemoline-d5: A metabolic probe for hyperactivity

✍ Scribed by Brian D. Andresen; Dan E. Weitzenkorn

Publisher
John Wiley and Sons
Year
1978
Tongue
French
Weight
326 KB
Volume
15
Category
Article
ISSN
0022-2135

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✦ Synopsis

The drug, pemoline-h, 2-imino-5-phenyl-&-4-oxazol idinone, was prepared by a f o u r step synthesis from benzene-&. synthetic sequence required the preparation o f dichloroacetophenone-&, mandelic acid-& and e t h y l mandelate-$. Mass spectral as well as i n f r a r e d data o f the l a b e l l e d drug are also presented.

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