𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of optically active α-(allenyl)- and α-substituted-α-(allenyl)glycines

✍ Scribed by Takuya Okada; Naoko Oda; Hiroyuki Suzuki; Kazuhiko Sakaguchi; Yasufumi Ohfune


Publisher
Elsevier Science
Year
2010
Tongue
French
Weight
488 KB
Volume
51
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


A facile synthesis of β-substituted-α-al
✍ James R McCarthy; Charlotte L Barney; Donald P Matthews; Thomas M Bargar 📂 Article 📅 1987 🏛 Elsevier Science 🌐 French ⚖ 244 KB

Copper or nickel catalyzed substitution of Grignard reagents on the bistrimethylsilyl protected 4-methoxy-2-butynylamine (2) provides B-substituted-a-allenyl primary amines (3) in high yield.

Efficient synthesis of optically active
✍ Masanori Kawasaki; Kosuke Namba; Hidekazu Tsujishima; Tetsuro Shinada; Yasufumi 📂 Article 📅 2003 🏛 Elsevier Science 🌐 French ⚖ 99 KB

Highly enantioselective synthesis of (2R)-a-(hydroxymethyl)glutamate (1), a selective agonist of mGluR2 and 3, was achieved in short steps using an asymmetric version of the Strecker synthesis. This was converted into its a-methoxymethyland a-benzyloxymethyl derivatives 2 and 3, possible ligands as