𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of Optically Active Prostaglandin-J2 and 15-Deoxy-Δ12,14-prostaglandin-J2.

✍ Scribed by Jamie F. Bickley; Vasudev Jadhav; Stanley M. Roberts; M. Gabriella Santoro; Alexander Steiner; Peter W. Sutton


Publisher
John Wiley and Sons
Year
2003
Weight
67 KB
Volume
34
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Expression of cyclooxygenase-2 and perox
✍ Alaa F. Badawi; Mostafa Z. Badr 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 193 KB 👁 1 views

## Abstract Cyclooxygenase‐2 (COX‐2) expression and peroxisome proliferator‐activated receptor‐γ (PPARγ) inactivation are linked to increased risk of human breast cancer. The purpose of our study was to examine the relationship between COX‐2 (with the resulting prostaglandins E~2~, PGE~2~) and PPAR

Involvement of c-jun N-terminal kinase a
✍ Jean-Dean Liu; Shyr-Yi Lin; Yuan-Soon Ho; Shiann Pan; Ling-Fang Hung; Shu-Huei T 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 224 KB

Cyclopentenone prostaglandins (CyPGs), derivatives of arachidonic acid, have been suggested to exert growth-inhibitory activity through peroxisome proliferator-activated receptor (PPAR)-dependent and -independent mechanisms. Here we examined various eicosanoids for growth inhibition and found that t

Effects of peroxisome proliferator-activ
✍ Steven A. Smith; Gregory R. Monteith; Nicola A. Holman; Jodie A. Robinson; Fiona 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 341 KB 👁 1 views

Peroxisome proliferator-activated receptor gamma (PPARgamma) has been the focus of studies assessing its potential neuroprotective role. These studies have shown either neuroprotection or neurotoxicity by PPARgamma ligands. Comparison of these studies is complicated by the use of different PPARgamma

Inhibition of interleukin-1β–induced cyc
✍ Katherine Farrajota; Saranette Cheng; Johanne Martel-Pelletier; Hassan Afif; Jea 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 313 KB 👁 1 views

Objective. The cyclooxygenase (COX) metabolite, 15-deoxy-⌬ 12,14 -prostaglandin J 2 (15d-PGJ 2 ), has been reported to inhibit the expression of a number of genes involved in the pathogenesis of arthritis. However, its effects on COX-2 remain controversial. We undertook this study to investigate the

15-deoxy-Δ12,14 prostaglandin J2 synergi
✍ E. Castaño; J. Gil 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 205 KB

## Abstract 15‐deoxy‐Δ^12,14^ prostaglandin J~2~ (15dPGJ~2~), a peroxisome proliferator‐activated receptor gamma (PPARγ) ligand, induced synergistic stimulation of DNA synthesis in the presence of phorbol dibutyrate (PDB) in Swiss 3T3 cells. This effect was dose‐dependent and the maximum response w