Synthesis of optically active penems
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V.M. Girijavallabhan; A.K. Ganguly; S.W. McCombie; P. Pinto; R. Rizvi
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Article
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1981
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Elsevier Science
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French
β 227 KB
A general synthesis for optically active penems is described. Penems undergo a novel thermal isomerisation reaction. Won-classical B-lactams, exemplified by thienamycin', olivanic acidl and the Woodward's novel synthetic "penem" have all been described as potent antimicrobial agents. Recently, Sever