Synthesis of Optically Active 5-( tert -Butyldimethylsiloxy)-2-cyclohexenone and Its 6-Substituted Derivatives as Useful Chiral Building Blocks for the Synthesis of Cyclohexane Rings. Syntheses of Carvone, Penienone, and Penihydrone
β Scribed by Hareau, Georges P-J.; Koiwa, Masakazu; Hikichi, Shinichi; Sato, Fumie
- Book ID
- 127285546
- Publisher
- American Chemical Society
- Year
- 1999
- Tongue
- English
- Weight
- 163 KB
- Volume
- 121
- Category
- Article
- ISSN
- 0002-7863
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π SIMILAR VOLUMES
Optically active trans-4-(tert-butyldimethylsiloxymethyl)-5-(tert-butyldimethylsiloxy)-2-cyclohexenone (2) has been synthesized in 25% overall yield starting from easily available 1,4-bis(benzyloxy)-2,3-epoxy butane (3). The enone 2 reacts with excellent stereoselectivity with RCu(CN)Li thus working
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