2,3-Didehydro-1,2-bis(methoxycarbonyl)-6-methoxypiperidine (4), prepared from l-lysine by using electrochemical oxidation, was cyclopropanated with high diastereoselectivity (96.6% de), and the cyclopropanated product was transformed to optically active 2,3-methanopipecolic acid (1). In this transfo
✦ LIBER ✦
Synthesis of optically active 2,3-methanopipecolic acid
✍ Scribed by Alain Hercouet; Bernard Bessières; Maurice Le Corre; Loïc Toupet
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- French
- Weight
- 157 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0040-4039
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