The first synthesis of bisdifluorocyclopropane derivatives has been accomplished via a chemo-enzymatic reaction strategy; (EF or (Z)-3-tributylstannyl-2-propenols were prepared and their conversion led to the (trans, trans)-and (cis, cis)-bisdifluorocyclopropanes. The subsequent lipase-catalyzed rea
β¦ LIBER β¦
Synthesis of optically active 2,3-dihydrobenzofuran derivatives through a combination strategy of iron(III)-catalyzed reaction and enzymatic reaction
β Scribed by Toshiyuki Itoh; Kimio Kawai; Shuichi Hayase; Hiroyuki Ohara
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- French
- Weight
- 299 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
Synthesis of optically active 2,3-dihydrofuran derivatives has been accomplished through a combination strategy of ferric ion-catalyzed cycloaddition of styrene derivatives with quinones and following lipase-catalyzed enantioselective acylation.
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