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Synthesis of optically active 2-arylalkanoic acids by the use of 1,2-rearrangement of the aryl group

โœ Scribed by Gen-ichi Tsuchihashi


Publisher
Elsevier Science
Year
1982
Tongue
French
Weight
197 KB
Volume
23
Category
Article
ISSN
0040-4039

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A new method for the synthesis of optically active a-hydroxyalkynylsilane 3 is described. The key step of the conversion to 3 was the use of the reverse Brook rearrangement of the 2-alkynyl silyl ether 2.