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Synthesis of oligonucleotides bearing the non-standard bases iso-C and iso-G. Comparison of iso-C-iso-G, C-G and U-A base-pair stabilities in RNA/DNA duplexes

✍ Scribed by Christopher Roberts; Rajanikanth Bandaru; Christopher Switzer


Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
188 KB
Volume
36
Category
Article
ISSN
0040-4039

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ModifiedG\*C,or A\*Ubase pairs havebeen incorporatedat the 4ti positionof a duplexcomposedwithnine basepairs.llre irrfluenceof these modificationson duplexstabilitieshas beenstudiedby absorptionspectrosco #. It has been formal that G4M'C has thermalstabilitysimilarto that of the AS\*U basepair. Thus