✦ LIBER ✦
Design of modified A*U and G*C base pairs with similar stability. Implication for the DNA sequencing by hybridization
✍ Scribed by Hong-Khanh Nguyen; Ulysse Asseline; Nguyen T. Thuong; Daniel Dupret
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 489 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
ModifiedG*C,or A*Ubase pairs havebeen incorporatedat the 4ti positionof a duplexcomposedwithnine basepairs.llre irrfluenceof these modificationson duplexstabilitieshas beenstudiedby absorptionspectrosco #. It has been formal that G4M'C has thermalstabilitysimilarto that of the AS*U basepair. ThusduplexesinvolvingG 'C or As-base pairs exhibitthe sameTm. @ 1997Elsevier Science Ltd.