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Synthesis of Novel Spiro Pyrano[2,3- d ]thiazolo[3,2- a ]pyrimidine via 1,3-Dipolar Cycloaddition of Azomethine Ylide

✍ Scribed by Ling, Yulin; Liu, Haochong; Zheng, Aiting; Li, Guobin; Li, Xiaofang

Book ID: 120660189
Publisher: Journal of Heterocyclic Chemistry
Year: 2013
Tongue: English
Weight: 635 KB
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.740

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## Abstract A new class of spiro thiazolo[3,2‐__a__]pyrimidine compounds were synthesized by the one‐pot sequential 1,3‐dipolar cycloaddition of azomethine ylide (generated from isatin and sarcosine)–nitrile oxide to 2‐arylmethylidene‐6,7‐dihydro‐5__H__‐thiazolo[3,2‐__a__]pyrimidin‐3‐ones in modera