✦ LIBER ✦

Synthesis of spiro thiazolo[3,2-a]pyrimidine compounds by one-pot sequential 1,3-dipolar cycloadditions

✍ Scribed by Xiaofang Li; Aiting Zheng; Bin Liu; Guobin Li; Xianyong Yu; Pinggui Yi

Publisher: Journal of Heterocyclic Chemistry
Year: 2011
Tongue: English
Weight: 95 KB
Volume: 48
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.578

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A new class of spiro thiazolo[3,2‐a]pyrimidine compounds were synthesized by the one‐pot sequential 1,3‐dipolar cycloaddition of azomethine ylide (generated from isatin and sarcosine)–nitrile oxide to 2‐arylmethylidene‐6,7‐dihydro‐5__H__‐thiazolo[3,2‐a]pyrimidin‐3‐ones in moderate yields. The structures of all the products were characterized thoroughly by NMR, MS, IR, elemental analysis, and NMR together with X‐ray crystallographic analysis. J. Heterocyclic Chem., (2011).

📜 SIMILAR VOLUMES

ChemInform Abstract: Synthesis of Spiro

ChemInform Abstract: Synthesis of Spiro Thiazolo[3,2-a]pyrimidines Compounds by One-Pot Sequential 1,3-Dipolar Cycloadditions.

✍ Xiaofang Li; Aiting Zheng; Bin Liu; Guobin Li; Xianyong Yu; Pinggui Yi 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 25 KB 👁 1 views

Synthesis of Novel Spiro Thiazolo[3,2-a]

Synthesis of Novel Spiro Thiazolo[3,2-a][1,3,5]triazines via 1,3-Dipolar Cycloaddition of Azomethine Ylide

✍ Xiaofang Li; Haochong Liu; Aiting Zheng; Zhikui Li; Guobin Li; Xianyong Yu; Ping 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 80 KB 👁 1 views

Unexpected 1,3-Dipolar Cycloaddition Rea

Unexpected 1,3-Dipolar Cycloaddition Reaction of Thiazolo[3,2-a]pyrimidine Derivatives and Nitrilimine

✍ Xiaofang Li; Haochong Liu; Bin Liu; Aiting Zheng; Guobin Li; Xianyong Yu; Pinggu 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 79 KB 👁 1 views

The 1,3-dipolar cycloaddition reactions of nitrilimine with thiazolo[3,2-a]pyrimidine derivatives was investigated. Bis-cycloadducts were obtained through a domino 1,3-dipolar cycloaddition/ring-opening/ring-opening/ 1,3-dipolar cycloaddition processes. The structures of the products were characteri

Synthesis of [1,2,4]Oxadiazolo[4,5-a]thi

Synthesis of [1,2,4]Oxadiazolo[4,5-a]thiazolo[2,3-b]pyrimidin-9(10H)-ones via 1,3-Dipolar Cycloaddition of Nitrile Oxide to Thiazolo[3,2-a]pyrimidin-3-one Derivatives

✍ Xiaofang Li; Aiting Zheng; Bin Liu; Xianyong Yu; Pinggui Yi 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 60 KB 👁 1 views

Synthesis of dispiro[oxindole-pyrrolidin

Synthesis of dispiro[oxindole-pyrrolidine]-thiazolo[3,2-a][1,3,5]triazines by 1,3-dipolar cycloaddition

✍ Xiaofang Li; Zhikui Li; Aiting Zheng; Guobin Li; Xianyong Yu; Pinggui Yi 📂 Article 📅 2011 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 119 KB

## Abstract The 1,3‐dipolar cycloaddition of an azomethine ylide generated by a decarboxylative route from sarcosine and isatin to 7‐arylmethylidene‐3‐aryl‐3,4‐dihydro‐2__H__‐thiazolo[3,2‐__a__][1,3,5]triazin‐6(7H)‐ones afforded novel dispiro[oxindole‐pyrrolidine]‐thiazolo[3,2‐__a__][1,3,5]triazine

ChemInform Abstract: Synthesis of Novel

ChemInform Abstract: Synthesis of Novel Spiro Thiazolo[3,2-a][1,3,5]triazines via 1,3-Dipolar Cycloaddition of Azomethine Ylide.

✍ Xiaofang Li; Haochong Liu; Aiting Zheng; Zhikui Li; Guobin Li; Xianyong Yu; Ping 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 29 KB 👁 1 views