𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of novel ferrocenylphosphine–amidine ligands and their application in Pd-catalyzed asymmetric allylic alkylation

✍ Scribed by Xiangping Hu; Huilin Chen; Xinquan Hu; Huicong Dai; Changmin Bai; Junwei Wang; Zhuo Zheng

Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
189 KB
Volume
43
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis

A family of novel ferrocenylphosphine-amidine ligands derived from (R)-(S)-PPFNH 2 -R 5 was applied to the palladium-catalyzed asymmetric allylic alkylation of 1,3-diphenylprop-2-en-1-yl acetate 8a or pivalate 8b with dimethyl malonate. Up to 94% e.e. was achieved when ligand 6b was used.

📜 SIMILAR VOLUMES

Synthesis of novel ferrocenylphosphine-a
Synthesis of novel ferrocenylphosphine-amidine ligands with central and planar chirality and their diastereomeric effect in Pd-catalyzed asymmetric allylic alkylation
✍ Xiangping Hu; Huilin Chen; Huicong Dai; Xinquan Hu; Zhuo Zheng 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 397 KB

Some novel ferrocenylphosphine-amidine ligands with central and planar chirality were prepared from (R,S p )-PPFNH 2 -R 3 and its diastereomer (S,S p )-PPFNH 2 3a. The efficiency and diastereomeric impact of these ferrocenylphosphine-amidine ligands in the palladium-catalyzed asymmetric allylic subs

Asymmetric Synthesis of Novel Ferrocenyl
Asymmetric Synthesis of Novel Ferrocenyl Ligands with Planar and Central Chirality and Their Application to Pd-Catalyzed Allylic Substitutions
✍ Dieter Enders; René Peters; René Lochtman; Gerhard Raabe; Jan Runsink; Jan W. Ba 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 923 KB

An efficient and flexible asymmetric synthesis of planar chiral ferrocenyl ligands bearing a stereogenic centre at the β-position to the metallocene backbone is described. A variety of donor groups can be independently introduced as electrophiles, thus allowing electronic and steric fine-tuning of t