Asymmetric Synthesis of Novel Ferrocenyl Ligands with Planar and Central Chirality and Their Application to Pd-Catalyzed Allylic Substitutions

✍ Scribed by Dieter Enders; René Peters; René Lochtman; Gerhard Raabe; Jan Runsink; Jan W. Bats

• Publisher: John Wiley and Sons
• Year: 2000
• Tongue: English
• Weight: 923 KB
• Volume: 2000
• Category: Article
• ISSN: 1434-193X
• DOI: 10.1002/1099-0690(200010)2000:20<3399::aid-ejoc3399>3.0.co;2-d

✦ Synopsis

An efficient and flexible asymmetric synthesis of planar chiral ferrocenyl ligands bearing a stereogenic centre at the β-position to the metallocene backbone is described. A variety of donor groups can be independently introduced as electrophiles, thus allowing electronic and steric fine-tuning of the ligands, which were investigated in Pd-catalyzed enanti-