✦ LIBER ✦

Synthesis of novel cyclic hydroxamic acids

✍ Scribed by Pabba Chittari; Achamma Thomas; Srinivasachari Rajappa

Publisher: Elsevier Science
Year: 1994
Tongue: French
Weight: 233 KB
Volume: 35
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)73101-7

No coin nor oath required. For personal study only.

✦ Synopsis

Abstrrrct: lk nitroacetyl (S)-proline esfers (Z,3,.5} are reduced by zinc-NH,Cl to the hydroxylamine stage and cyclized toprovide the novel chit-al bicyclic hydroxamic acids (2,4,6). Michael addition of ally1 acrylate on nhmacetic acid derivatives followed by Pd(0) catalyzed intramolecular ally1 transfer and subsequent reduction of the nib-o group yielded a novel class of cyclic hydroxamic acidr related to pyroglutamic acid

Hydroxamic acids constitute an important class of siderophores, which play a major role in iron-solubilixation and transport'. Some of these compounds have already found application as therapeutic

📜 SIMILAR VOLUMES

Unsaturated heterocyclic systems—XVI : A

Unsaturated heterocyclic systems—XVI : A novel synthesis of cyclic hydroxamic acid esters

✍ L.A. Paquette 📂 Article 📅 1966 🏛 Elsevier Science 🌐 French ⚖ 345 KB

Synthesis of novel α-keto hydroxamic aci

Synthesis of novel α-keto hydroxamic acids

✍ Saïd Boukhris; Abdelaziz Souizi; Albert Robert 📂 Article 📅 1998 🏛 Elsevier Science 🌐 French ⚖ 109 KB

ChemInform Abstract: Synthesis of Novel

ChemInform Abstract: Synthesis of Novel α-Keto Hydroxamic Acids.

✍ S. BOUKHRIS; A. SOUIZI; A. ROBERT 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 1 views

ChemInform Abstract: An Improved Synthes

ChemInform Abstract: An Improved Synthesis of Cyclic Hydroxamic Acids from Gramineae.

✍ K. TAYS; J. ATKINSON 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 30 KB 👁 2 views

Cyclic steroidal hydroxamic acid derivat

Cyclic steroidal hydroxamic acid derivatives

✍ Hwalin Lee; Manfred E. Wolff 📂 Article 📅 1967 🏛 Elsevier Science 🌐 French ⚖ 188 KB

On oxidation of 18-oximino-20-hydroxypregnane derivatives with sodium z-chlorobenzenesulfonamide (chloramine B) (CB), Hora (1) reported that 6'methyl-tetrahydro-1'2'-oxaaino-(4',5': 135, 178

Solid supported synthesis of hydroxamic

Solid supported synthesis of hydroxamic acids

✍ Adam Golebiowski; Sean Klopfenstein 📂 Article 📅 1998 🏛 Elsevier Science 🌐 French ⚖ 185 KB

A novel approach to the solid supported synthesis of hydroxamic acids was developed. It employs oxime resin and unlike all previously reported methods allows for the use of acid labile protecting groups. Cleavage is induced by treatment with tert-butyldimethylsilyl-O-hydroxylamine, followed by silyl