Synthesis of novel chiral dopants based on optically active p-substituted mandelic acids
✍ Scribed by Andreja Lesac; Sanja Narančić; Maja Šepelj; Duncan W. Bruce; Vitomir Šunjić
- Book ID
- 104360036
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 339 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0957-4166
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📜 SIMILAR VOLUMES
The (R)-2-(adenin-9-yl)propanoic acid 2 was prepared from adenine and (S)-ethyl lactate by using the triphenyl phosphine-diethyl azodicarboxylate system. The (R)-2-(thymin-l-yl)propanoic acid, (R)-2-(cytosin-l-yl)propanoic acid, and (R)-2-(hypoxanthin-9-yl)propanoic acid were also prepared.
## Abstract Summary: A diastereomeric pair of novel __N__‐propargylphosphonamidates, HCCCH~2~NHP(O)(CH~3~)O‐L‐menthyl was synthesized by the successive condensations of methylphosphonic dichloride with L‐menthol and propargylamine. The (__R__)‐P‐isomer (1a) was isolated, and the absolute configur