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Synthesis of Novel Cationic Lipids Having Polyamidoamine Dendrons and Their Transfection Activity

✍ Scribed by Takahashi, Toshinari; Kono, Kenji; Itoh, Toshihide; Emi, Nobuhiko; Takagishi, Toru


Book ID
121274115
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
220 KB
Volume
14
Category
Article
ISSN
1043-1802

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## Abstract In an effort to enhance the gene‐transfer efficiencies of cationic lipids and to decrease their toxicities, a series of new phosphoramidate lipids with chemical similarity to cell membrane phospholipids was synthesised. These lipids contained various cationic headgroups, such as arginin