𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of Novel Benzoic Acid Derivatives with Benzothiazolyl Subunit and Evaluation as Aldose Reductase Inhibitors

✍ Scribed by Dietmar Rakowitz; Barbara Hennig; Marietta Nagano; Stefan Steger; Luca Costantino; Barbara Matuszczak


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
114 KB
Volume
338
Category
Article
ISSN
0365-6233

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


On the Synthesis of Bioisosters of O-Ben
✍ Dietmar Rakowitz; Patric Muigg; Nicole SchrΓΆder; Barbara Matuszczak πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 115 KB πŸ‘ 1 views

## Abstract In continuation of our attempts to develop novel aldose reductase inhibitors (ARIs), a number of compounds characterized by bioisosteric replacement of pharmacophors were prepared. On the one hand, the acidic function was formally replaced by an oxime or a nitro group and on the other h

Synthesis and Biological Evaluation of 4
✍ Ola I. A. Salem; Tobias Schulz; Rolf W. Hartmann πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 115 KB πŸ‘ 2 views

The synthesis and biological evaluation of 4-(4-(alkyl- and phenylaminocarbonyl)benzoyl)benzoic acids (4a-4d) as non-steroidal inhibitors of steroid 5 alpha-reductase are described. The compounds were tested in vitro for inhibitory activity toward rat and human 5 alpha-reductase isozymes 1 and 2 at