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Synthesis of novel 5-aryl-6-cyano-3H,8H-pyrido[2,3-d]pyrimidine-4,7-diones in the reaction of 6-amino-4-pyrimidinones with benzaldehyde and ethyl cyanoacetate

✍ Scribed by Jairo Quiroga; Mario Alvarado; Braulio Insuasty; Manuel Nogueras; Adolfo Sánchez; M. Dolores López


Publisher
Journal of Heterocyclic Chemistry
Year
1999
Tongue
English
Weight
202 KB
Volume
36
Category
Article
ISSN
0022-152X

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ChemInform Abstract: Reactivity of Thioa
✍ K. HIROTA; K. KUBO; H. SAJIKI; Y. KITADE; M. SAKO; Y. MAKI 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 1 views

## Reactivity of Thioaldehyde: Cyclization Reaction of 6-Amino-1,3-dimethyl-5-thioformyluracil with Enamines into Pyrido(2,3d)pyrimidine-2,4-(1H,3H)-diones. -The thioaldehyde (I) reacts with electron-rich morpholino enamines under mild condition to afford pyridopyrimidines of type (III) in a regi