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Synthesis of novel 3,5,7-triaryl-5,6-dihydro-4h-1,2,5-triazepines

✍ Scribed by Gurusamy Ravindran; Shanmugam Muthusubramanian; Sanguvan Selvaraj; Subbu Perumal

Publisher: Journal of Heterocyclic Chemistry
Year: 2007
Tongue: English
Weight: 377 KB
Volume: 44
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570440121

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✦ Synopsis

Several hitherto unknown 3,5,7-triaryl-5,6-dihydro-4H-1,2,5-triazepines have been synthesised by cyclocondensation of N,N-bis(phenacyl)anilines with hydrazine hydrate in ethanol or ethyleneglycol under reflux condition. Increased yields were obtained in the presence of p-toluenesulfonic acid compared to the uncatalysed reaction.

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