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Synthesis of novel 3-carboxamide-benzocoumarin derivatives as orally active antithrombotic agents

โœ Scribed by Koneni V. Sashidhara; Abdhesh Kumar; Manoj Kumar; S. Singh; Manish Jain; Madhu Dikshit


Book ID
113496224
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
595 KB
Volume
21
Category
Article
ISSN
0960-894X

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โœ Koneni V. Sashidhara; Jammikuntla N. Rosaiah; Manoj Kumar; Rishi Kumar Gara; Lak ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 604 KB

A small library of novel benzocoumarin derivatives based on naturally occurring neo-tanshinlactone scaffold was constructed and their antiproliferative activities against breast cancer cells MCF-7 and MDA-MB-231 were evaluated. A number of derivatives showed good anti-breast cancer activity, in some