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Discovery and synthesis of novel substituted benzocoumarins as orally active lipid modulating agents

โœ Scribed by Koneni V. Sashidhara; Manoj Kumar; Ram K. Modukuri; Anuj Srivastava; Anju Puri


Book ID
113496188
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
952 KB
Volume
21
Category
Article
ISSN
0960-894X

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โœ Koneni V. Sashidhara; Jammikuntla N. Rosaiah; Manoj Kumar; Rishi Kumar Gara; Lak ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 604 KB

A small library of novel benzocoumarin derivatives based on naturally occurring neo-tanshinlactone scaffold was constructed and their antiproliferative activities against breast cancer cells MCF-7 and MDA-MB-231 were evaluated. A number of derivatives showed good anti-breast cancer activity, in some