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Synthesis of novel 2-phenyl-3-[2-(substituted amino) ethylamino] quinazolin-4(3H)-ones as a new class of H1-antihistaminic agents

✍ Scribed by V. Alagarsamy, P. Shyam Sundar, M. Gobinath, S. Nivedhitha…


Book ID
120908605
Publisher
Springer-Verlag
Year
2012
Tongue
English
Weight
303 KB
Volume
22
Category
Article
ISSN
1054-2523

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✍ V. Alagarsamy; P. Parthiban; V. Raja Solomon; K. Dhanabal; S. Murugesan; G. Sara 📂 Article 📅 2008 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 312 KB

## Abstract magnified image A series of novel 4‐(4‐ethylphenyl)‐1‐substituted‐4__H__‐[1,2,4]triazolo[4,3‐__a__]quinazolin‐5‐ones were synthesized by the cyclization of 2‐hydrazino intermediate with various electrophile. The starting material 2‐hydrazino compound was synthesized from 2‐ethyl anilin