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Synthesis and pharmacological investigation of novel 1-substituted-4-(4-substituted phenyl)-4H-[1,2,4]triazolo[4,3-a]quinazolin-5-ones as a new class of H1-antihistamine agents

✍ Scribed by V. Alagarsamy; Rajani Giridhar; M. R. Yadav


Book ID
111770591
Publisher
Pharmaceutical Press
Year
2006
Tongue
English
Weight
327 KB
Volume
58
Category
Article
ISSN
2042-7158

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Synthesis and pharmacological investigat
✍ V. Alagarsamy; P. Parthiban; V. Raja Solomon; K. Dhanabal; S. Murugesan; G. Sara πŸ“‚ Article πŸ“… 2008 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 312 KB

## Abstract magnified image A series of novel 4‐(4‐ethylphenyl)‐1‐substituted‐4__H__‐[1,2,4]triazolo[4,3‐__a__]quinazolin‐5‐ones were synthesized by the cyclization of 2‐hydrazino intermediate with various electrophile. The starting material 2‐hydrazino compound was synthesized from 2‐ethyl anilin