Synthesis of nontrivial quinopimaric acid derivatives by oxidation with dimethyldioxirane
โ Scribed by Oxana B. Kazakova; Elena V. Tretyakova; Olga S. Kukovinets; Albina R. Abdrakhmanova; Nataliya N. Kabalnova; Dmitri V. Kazakov; Genrikh A. Tolstikov; Aidar T. Gubaidullin
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- French
- Weight
- 384 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0040-4039
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๐ SIMILAR VOLUMES
The dwzt oxldatron of enolates with &methylchoxirane ( as a solunon m acetone ) provides the ahydroxy &nvanves m excellent yield The converSlon of enohzable ketones to their correspondmg a-hydroxy denvatlves 1s an important synthenc transformanon and has received a great deal of attennon la2 The cl
Using dimethyldioxirane, the selective transformation of aldehyde N,N-dimethylhydrazones into the corresponding nitriles was achieved in high yield and under mild conditions. The determination of the substituent effect on rates, along with an estimate of the primary kinetic isotope effect using PhCH