✦ LIBER ✦

Synthesis of Non-nucleoside Analogs of Toyocamycin, Sangivamycin, and Thiosangivamycin: The Effect of Certain 4- and 4,6-Substituents on the Antiviral Activity of Pyrrolo[2,3- d ]pyrimidines

✍ Scribed by Renau, Thomas E.; Kennedy, Christopher; Ptak, Roger G.; Breitenbach, Julie M.; Drach, John C.; Townsend, Leroy B.

Book ID: 124050142
Publisher: American Chemical Society
Year: 1996
Tongue: English
Weight: 234 KB
Volume: 39
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm950835y

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

ChemInform Abstract: Synthesis of Non-Nu

ChemInform Abstract: Synthesis of Non-Nucleoside Analogues of Toyocamycin, Sangivamycin, and Thiosangivamycin: The Effect of Certain 4- and 4,6-Substituents on the Antiviral Activity of Pyrrolo(2,3-d)pyrimidines.

✍ T. E. RENAU; C. KENNEDY; R. G. PTAK; J. M. BREITENBACH; J. C. DRACH; L. B. TOWNS 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB

Synthesis, cytotoxicity, and antiviral a

Synthesis, cytotoxicity, and antiviral activity of some acyclic analogs of the pyrrolo[2,3-d]pyrimidine nucleoside antibiotics tubercidin, toyocamycin, and sangivamycin

✍ Gupta, Pranab K.; Daunert, Sylvia; Nassiri, M. Reza; Wotring, Linda L.; Drach, J 📂 Article 📅 1989 🏛 American Chemical Society 🌐 English ⚖ 944 KB

Synthesis, cytotoxicity, and antiviral a

Synthesis, cytotoxicity, and antiviral activity of certain 7-[(2-hydroxyethoxy)methyl]pyrrolo[2,3-d]pyrimidine nucleosides related to toyocamycin and sangivamycin

✍ Gupta, Pranab K.; Nassiri, M. Reza; Coleman, Lisa A.; Wotring, Linda L.; Drach, 📂 Article 📅 1989 🏛 American Chemical Society 🌐 English ⚖ 841 KB

ChemInform Abstract: Synthesis of Non-Nu

ChemInform Abstract: Synthesis of Non-Nucleoside Analogues of Toyocamycin, Sangivamycin, and Thiosangivamycin: Influence of Various 7-Substituents on Antiviral Activity.

✍ T. E. RENAU; L. L. WOTRING; J. C. DRACH; L. B. TOWNSEND 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 34 KB

Synthesis and antiviral activity of some

Synthesis and antiviral activity of some 7-[(2-hydroxyethoxy)methyl]pyrazolo[3,4-d]pyrimidine analogs of sangivamycin and toyocamycin

✍ Saxena, Naveen K.; Coleman, Lisa A.; Drach, John C.; Townsend, Leroy B. 📂 Article 📅 1990 🏛 American Chemical Society 🌐 English ⚖ 608 KB

Synthesis of Non-Nucleosides: 7- and 1,3

Synthesis of Non-Nucleosides: 7- and 1,3-Substituents of New Pyrrolo[2,3-d]pyrimidin-4-ones on Antiviral Activity

✍ Khalid Mohammed Hassan Hilmy 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 516 KB

## Abstract A series of non‐nucleosides **9–47** were synthesized. Compounds **1–4** were reacted with formic acid (85%) to afford compounds **5‐8**. Then, the latter compounds were reacted with alkyl halides **a–f** (2‐bromopropane, 2‐bromobutane, benzyl bromide, benzyl chloromethyl ether, chlorom