Synthesis of Nitrogen Heterocycles by th
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Aaron M. Kearney; Christopher D. Vanderwal
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Article
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2006
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John Wiley and Sons
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English
β 117 KB
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The ring-opening reaction of pyridinium salts dates back over a century to the pioneering work of Zincke and KΓΆnig. [1] Activation of pyridines as their pyridinium salts renders the heterocycle electrophilic at the 2-and 4-positions and enables a diverse range of productive chemistry, with or withou