Synthesis of Nitro-Substituted 4-Oxo-4H-pyrimido[2,1-b]benzothiazole-3-carboxylic Acids and Their Spectral Characteristics
✍ Scribed by Bartovič, Alexander; Ilavský, Dušan; Šimo, Ondrej; Zalibera, Lubomír; Belicová, Anna; Seman, Milan
- Book ID
- 120641365
- Publisher
- UOCHB
- Year
- 1995
- Tongue
- English
- Weight
- 97 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0010-0765
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## Abstract Reaction of 4__H__‐pyrimido[2,1‐__b__]benzothiazole‐2‐thiomethyl‐3‐cyano‐4‐one **(1)** with hydrazine hydrate/aryl hydrazine/heteryl hydrazine in the presence of anhydrous potassium carbonate and dimethyl formamide afforded 3‐amino‐4‐oxo‐(2__H__)/aryl/heteryl pyrazolo[3′,4′:4,5]pyrimido
## Abstract 2‐Amino‐6‐methoxybenzothiazole **1** on reaction with bis(methylthio)methylene malononitrile **2** in the presence of dimethyl formamide and catalytic amount of anhydrous potassium carbonate afforded 3‐cyano‐4‐imino‐8‐methoxy‐4__H__‐pyrimido[2,1‐__b__][1,3]benzothiazole **3**. Under sim