✦ LIBER ✦

Novel Synthesis of 3-Amino-4-oxo-(2H)-pyrazolo[3′,4′:4,5]pyrimido-[2,1-b]benzothiazole and its 2- and 3-Substituted Derivatives

✍ Scribed by K. G. Baheti; S. V. Kuberkar

Publisher: Journal of Heterocyclic Chemistry
Year: 2003
Tongue: English
Weight: 41 KB
Volume: 40
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570400322

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Reaction of 4__H__‐pyrimido[2,1‐b]benzothiazole‐2‐thiomethyl‐3‐cyano‐4‐one (1) with hydrazine hydrate/aryl hydrazine/heteryl hydrazine in the presence of anhydrous potassium carbonate and dimethyl formamide afforded 3‐amino‐4‐oxo‐(2__H__)/aryl/heteryl pyrazolo[3′,4′:4,5]pyrimido[2,1‐b]benzothiazoles in good yield. These pyrazole derivatives on diazotization followed by replacement with hydroxy, chloro, bromo, iodo and on reduction gave the corresponding 3‐substituted derivatives.

📜 SIMILAR VOLUMES

Novel Synthesis of 3-Amino-4-oxo-(2H)-py

Novel Synthesis of 3-Amino-4-oxo-(2H)-pyrazolo[3′,4′;4,5]pyrimido[2,1-b]benzothiazole and Its 2- and 3-Substituted Derivatives.

✍ K. G. Baheti; S. v. Kuberkar 📂 Article 📅 2003 🏛 John Wiley and Sons ⚖ 133 KB 👁 1 views

Novel synthesis and biological activity

Novel synthesis and biological activity of 2-substituted derivatives of 3-cyano-4-imino-2-methylthio-8-methoxy-4H-pyrimido[2,1-b][1,3]benzothiazole and 3-amino-4-imino-8-methoxy-2H-pyrazolo[3′,4′:4,5]pyrimido[2,1-b][1,3]benzothiazole

✍ S. G. Badne; D. K. Swamy; V. N. Bhosale; S. V. Kuberkar 📂 Article 📅 2011 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 183 KB

## Abstract 2‐Amino‐6‐methoxybenzothiazole **1** on reaction with bis(methylthio)methylene malononitrile **2** in the presence of dimethyl formamide and catalytic amount of anhydrous potassium carbonate afforded 3‐cyano‐4‐imino‐8‐methoxy‐4__H__‐pyrimido[2,1‐__b__][1,3]benzothiazole **3**. Under sim

ChemInform Abstract: Novel Synthesis and

ChemInform Abstract: Novel Synthesis and Biological Activity of 2-Substituted Derivatives of 3-Cyano-4-imino-2-methylthio-8-methoxy-4H-pyrimido[2,1-b] [1,3]benzothiazole and 3-Amino-4-imino-8-methoxy-2H-pyrazolo[3′,4′:4,5]pyrimido[2,1-b] [1,3]benzothiazole.

✍ S. G. Badne; D. K. Swamy; V. N. Bhosale; S. V. Kuberkar 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 40 KB 👁 2 views

Synthesis of Certain 3-Aminopyrazolo[5,4

Synthesis of Certain 3-Aminopyrazolo[5,4-b]pyridine and 3,4-Substituted Pyrido[2′,3′ :3,4]pyrazolo[5,1-c][1,2,4]triazine Derivatives

✍ Ali Khader Khalil EL-LOUH; Nada Mohamed ABUNADA; Mohamed EL-SHOUBAKI 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 71 KB 👁 1 views

A Convenient Synthesis of 2,3-Disubstitu

A Convenient Synthesis of 2,3-Disubstituted Derivatives of 4H-Pyrimido[2,1-b]benzothiazole-4-one.

✍ K. G. Baheti; S. B. Kapratwar; S. V. Kuberkar 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB 👁 1 views

ChemInform Abstract: A Facile Synthesis

ChemInform Abstract: A Facile Synthesis of Pyrimido[2′′,3′′:5′,1′]pyrazolo[3′,4′:4,5]pyrimido[1,6-a]benzimidazoles and [1,2,4]Triazino[3′′,4′′:5′,1′] pyrazolo [3′,4′:4,5] -pyrimido[6,1-a]benzimidazoles.

✍ Abdou O. Abdelhamid; Hussein F. Zohdi; Mahmoud M. Ziada 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 36 KB 👁 1 views