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Synthesis of new xanthenone derivatives of expected antibilharzial activity

โœ Scribed by Mahmoud T. Omar

Book ID
105672213
Publisher
Springer
Year
1997
Tongue
English
Weight
673 KB
Volume
20
Category
Article
ISSN
0253-6269

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Synthesis of New Xanthene Derivatives wi
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โœ Zeid, Ibrahim ;El-Kousy, Salah ;El-Torgoman, Abdel Moneim ;Ismail, Abdel Hamid ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 188 KB

N-(9H-Xanthen-9-yl)succinimide (1) is prepared by the reaction of xanthene with N-bromosuccinimide. Hydrolysis of 1 with 5% NaOH yields 3-[(9H-xanthen-9-yl)inocarbonyl]propionic acid (3a). The corresponding methyl ester 3c is obtained from 3a by the action of diazomethane. The butanol derivative 4a