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Synthesis of new triphenodithiazine- and indolocarbazolediones of biological interest

✍ Scribed by A. S. Hammam; M. S. K. Youssef; F. M. Atta; Th. A. Mohamed

Book ID
111491061
Publisher
Versita
Year
2007
Tongue
English
Weight
185 KB
Volume
61
Category
Article
ISSN
0366-6352

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✦ Synopsis

Abstract

Tetrabromo-p-benzoquinone reacted with excess aromatic amines to give 2,5-dirylamino-3,6-dibromo-p-benzoquinones. The latter molecules on heating with sodium sulfide in alcohol in the presence of air gave triphenodithiazinediones. Heating with copper powder in nitrobenzene transformed these compounds into the respective indolocarbazolediones. Comparative antimicrobial and antifungal activities of the studied compounds were determined and discussed.

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