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Synthesis of new substrate of exonuclease A5

✍ Scribed by I. A. Kozlov; R. K. Ledneva; T. N. L'vova; R. I. Tatarskaya


Book ID
112437102
Publisher
Springer
Year
1974
Tongue
English
Weight
197 KB
Volume
23
Category
Article
ISSN
1573-9171

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The Substrate Specificity of Exonuclease
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Synthesis and study of a new adenine–acr
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A new heterodimer adenine-chain-acridine containing a mixed amido-guanidinium linker chain was synthesized. To achieve the synthesis a new method of introduction of aminoalkyl chain at position 9 of adenine was designed. The heterodimer interacts specifically with the abasic sites in DNA and inhibit