Synthesis of new series of N-3-[-{2-(substituted phenyl-4-oxo-5-(substituted benzylidene)-1,3-thiazolidine}-carbamyl]-propyl-2-aminothiazole and their biological importance
✍ Scribed by PUSHKAL SAMADHIYA, RITU SHARMA, SANTOSH K SRIVASTAVA, SAVITRI D SRIVASTAVA
- Book ID
- 113094082
- Publisher
- Indian Academy of Sciences,Royal Society of Chemistry
- Year
- 2011
- Tongue
- English
- Weight
- 274 KB
- Volume
- 123
- Category
- Article
- ISSN
- 0253-4134
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Synthesis and Pharmacological Activity of 2-(Substituted Phenyl)-3-(2 or 3-((4-Substituted Phenyl-4-hydroxy)piperidino)ethyl or propyl)-1,3-thiazolidin-4-ones. -A new series of 1,3-thiazolidinone analogues of loperamide (cf. (IV), 10 examples) are synthesized and evaluated for their antidiarrheal a
## Abstract Synthesis of 3‐(3‐nitrophenacyl)thiazolidine‐2,4‐dione **2g** and 3‐(substituted phenacyl)‐5‐[3′‐(4__H__‐4‐oxo‐1‐benzopyran‐2‐yl)‐benzylidene]‐2,4‐thiazolidinediones **4a–g** are reported in this paper. These compounds **4a–g** were prepared from 3′‐flavone carboxaldehyde and 3‐substitu