Synthesis of New Quinazoline Derivatives of Expected Potential Bioresponses.
✍ Scribed by Yvette A. Isaac; Mona H. Arsanious; HIsham A. Abd. El-Nabi
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 156 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
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## Abstract Some derivatives of quinazoline and 1, 2‐dihydroquinazoline __N__^3^‐oxide were synthesised and their cytotoxic activities against human leukaemia HL‐60 cells under hypoxic and aerobic conditions were tested and compared to tirapazamine as the reference compound. Compound 8 showed 5‐fol
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